Obesity, weight reduction and NASH among type 2 diabetics

Medicollect has gathered answers from 2.247 members with type 2 diabetes of its Danish Research Panel (forskningspanelet.dk). The survey was conducted online 29.-31. January 2018. And we would like to share the results with you.

Type 2 diabetes and overweight are closely connected. But to what extend? What is the average BMI for a person diagnosed with type 2 diabetes? The answer is 31.4.

BMI among type 2 diabetics – distribution in weight classes



But what do people do about their overweight? This issue is approached with two questions.

Have you within the last year reduced your weight with 10 kilos or more?


Have you undergone a weight reduction gastric bypass?



There is an increased focus on Non Alcoholic Fatty Liver Disease (NAFLD) and particularly the more serious version NASH (Non Alcoholic Steatohepatitis). Not only because the prevalence is estimated to have doubled since 2000, but also because new treatments are being developed.

NASH is a silent disease, i.e it shows no symptoms. Therefor it is seldom diagnosed. The prevalence of NASH is widely discussed, estimates range from 2-5% of the adult population. The disease is much more common among type 2 diabetics (40% of all NASH patients have diabetes). But the question is, how many type 2 diabetics are actually diagnosed with NASH?

Have you been diagnosed with Non Alcoholic Liver Disease, NAFLD or NASH?



Only 17 out of 2.247 (1,3%) type 2 diabetics report having a NASH/NAFLD diagnose. This is considerably lower than the estimated prevalence among type 2 diabetics (10-15%).

So the conclusion is, that only 1 out of 10 NASH patients (among type 2 diabetics) are diagnosed.



The development of new medicines lies in the hands of nurses

Nurses play a vital role in clinical research from recruitment and screening of patients to performing the clinical trial and documenting research results. Their work is hugely underrated, and the long overdue acknowledgement comes from an unexpected partner.

Every day, study nurses at hospitals around the world make huge efforts to conduct clinical research aimed at improving medical treatment for patients.  But conducting clinical research is a tough struggle of work-resources and time. Increasingly complex studies have made it necessary for study nurses to improve the patient recruitment processes.

Therese Hansen, 44 years old, is a Danish study nurse at the research department at Holbæk Sygehus. She knows the consequences of sites failing to recruit patients for a clinical study;

“We use many resources starting a clinical study. If we haven’t found a patient within two months, it’s highly possible that the clinical study will be shut down. This is a direct consequence for us, the site personal. But another consequence is, that there will not be developed any new and better medicine for the patients.”

Site engagement as a new strategy

When Medicollect, a patient recruitment specialist, identified the crucial role study nurses play in modern clinical research, they decided to take a drastic step: The strategy of the entire company was changed.

Medicollect’s CEO, Rene Ludwigs explains: “The moment we realized how important study nurses are for future medical development, it was clear to us that we needed to engage with them and learn from them. We hired an experienced study nurse as Site Relations Manager, and her direct engagement with site personnel provides crucial insights on their everyday challenges with patient recruitment; insights we use to guide our development”.

One of the first learning’s from engaging directly with study nurses, was their need for easy access to patients with a high probability of enrollment. By focusing on relieving study nurses from the time consuming task of identifying patients for enrollment, Medicollect works as a partner more than a supplier.

Medicollect’s new Site Relations Manager, Birgit Hauggaard-Nielsen is excited that she can use her experience as study nurse to improve the patient recruitment process. “I know about the challenges site nurses face every day, especially when it comes to patient recruitment. Therefor I’m excited to work with site engagement in my new position at Medicollect, because we can support and assist study nurses with a time consuming task, and ultimately make their work a lot easier”.

Nurses welcome new digital too

One of the Danish hospitals partnering with Medicollect is Holstebro Sygehus. Karen Devantier works as a study nurse at the medical research department, and she has had first hand experience receiving patients from Medicollect.

It’s the first time that we are working together with an external company, but I think that it’s great. Medicollect delivers patients who are committed and ready to participate in clinical trials, and the patients are very easy to contact. This ultimately makes my job as study nurse much easier”, says Karen.

And she expresses equal excitement with Medicollect’s digital enrollment system, called Enroller. Through this pre-screened patients with a high probability for enrollment are made accessible for study nurses with each patients’ medical- and contact information ready at hand.

Enroller is brilliant! It’s easy to use and I can quickly access the patients’ contact information. I would describe the system as user-friendly. It helps me get a quick access to all the information that I need, so I can get in contact with the pre-screened patients quickly”, Karen adds.

A new patient recruitment partner

Both Karen and Therese think that there are many upsides for partnering up with Medicollect, and that Medicollect’s focus on site engagement makes the difference.

Earlier, we have tried to recruit patients for clinical trials by advertising in the papers, but that didn’t pay off. I think that working with Medicollect is an easier, more efficient and better way to recruit patients”, says Karen.

Do you want to know more about Medicollect?

Then contact COO, Torben Lind, torbenlind@medicollect.dk or  +45 40 44 38 53

Dedicated focus on relations with site personnel

In order to build upon Medicollect’s great relations with site personnel, Medicollect has decided to hire two dedicated Site Relations Managers, responsible for communication with research nurses and investigators at sites in Denmark and United Kingdom.

For quite a while, we have been looking for people with strong communication skills, thorough understanding of the challenges faced by site personnel, and an empathetic personality. I am happy to say that we have succeeded”, says Medicollect’s CEO, Rene Vind Ludwigs.

The British Site Relations Manager, Cassie Merenick is an experienced nurse with several health care competencies from both Canada and Sweden. She has been involved  with research projects throughout  her career.  She has extensive knowledge about the work day as a nurse and insights on strongholds, and the challenges site personnel face.

I know how difficult it is to find the patients needed for modern clinical trials. Protocols are becoming increasingly specific, with narrowing participation criteria. This, in turn, leads to greater patient recruitment challenges. Finding the time and resources to recruit patients is becoming a  heavier burden for site personnel”, Cassie Merenick explains.

And she continues:
This position as Site Relations Manager, is like a dream come true  professionally. I have always wanted to combine my competencies within clinical research while meeting patient’s needs. At Medicollect I have the opportunity to achieve this rare and unique combination. It makes me very proud and enthusiastic”.

Want to know more about Medicollect’s focus on site relations?

Contact Torben LInd at torbenlind@medicollect.dk

Facts on Medicollect

  • Patient Recruitment Organisation (PRO) since 2012
  • Recruiting patients in Europe across all diseases